Distillation and Terpenes Isolation

This is for information & educational purposes only:

Wipe Film Evaporator Units are a special type of short-path, molecular distillation equipment. These are continuous mode systems, as opposedto batch vessel distillation apparatus. The diagram below of the cannabinoid purification distillation process illustrates the means of this technology and shows the flow of the feed material and the separation of component fractions within the equipment.

Operating Description

Wipe Film Evaporator Units consist of a heated body into which a fluid system requiring some degree of separation is continuously fed. The fluid is spread into a thin film by a rotating wiper blade assembly driven at a predetermined speed. The film, while being forced into turbulentflow by the wiper blades, progresses down the inside body wall aided by gravity and the slots in the wiper blades. Wiper Blades move each plug of material around and downward

During the course of flow through the heater system, some degree of evaporation takes place depending upon the characteristics of the feed material and the inside wall temperature, in addition to the system pressure. The non evaporated fluid forming the bottom product flows out of the system continuously while the vapor is condensed either inside or outside the system depending on the type of design.

Turbulence and micromixing created by a rapidly moving diagonally slotted blade greatly assists in heat transmission, thereby lowering the temperature required on the inside evaporator wall for a given system pressure. A maximum resulting surface area per unit volume of Dow is generated, facilitating rapid, eucient evaporation.

The liquid exposure time to the elevated wall temperature can becontrolled and also completed within a matter of seconds. This minimizes product degradation of heat sensitive materials by controlling the wiper assembly speed. Diagonally slotted wiper blades promote plug flow with little back mixing and direct motion both circumferentially and downward. This minimizes dwell time distribution, ensuring that material flowing through the system has a uniform exposure to process conditions.

Feed material is delivered from a feed flask into a cylindricalevaporation section, having heating, on the outside, (either electric resistance or circulating hot oil jacket type), and a diagonally slotted wiper mechanism forcing liquid around and downward in a thin film on the inside. In the center of the body is a closely positioned internal condenser, providing a short path for vapor molecules traveling from the heated surface to the condenser surface. For cannabinoids, the internal condenser fluid must be kept elevated (~70°C) to prevent high viscosity or freeze up of THC, CBD and related components. During the journey downward, lighter (lower boiling point) fractions of the liquid begin to vaporize, move to the internal condenser and condense, falling down as a liquid into a well that captures and separates the distilled liquid (cannabinoid) which flows into a receiver flask. Heavier residue material (Chlorophyll, salts, sugars, heavy wax fractions) does not evaporate and instead travels the length of the still body and flows into a different receiver flask. This all happens within a number of seconds, and under vacuum-lowered temperatures, thus minimizing any possibility of product degradation.

While Cannabinoids are caught and collected by the internal condenser, a different, external condenser, maintained at a chilled temperature, can capture terpenes (which are lighter than cannabinoids). The isolatedterpenes are then collected in another, separate receiver flask. Depending on the composition of the feed material and the goals of the operator, some quantities of different terpenes are obtainable which can be very useful for various product formulations. Any remaining vapors which escape both the internal and external condensers and which may contain small amounts of solvents, water or lighter terpenecomponents, are collected in a cold trap maintained at an ultra-low temperature. The trap serves the purpose of maintaining lowered vacuum levels in the still system and protecting the vacuum pump from contamination from the light vapors.

It is important to maintain a steady feed rate, body temperature and vacuum level. In the standard glass molecular still systems, feed rate and vacuum are maintained manually. Advanced Synthesis can also provide positive displacement feed pumps, automatic flow rate controllers, automatic vacuum controllers and other advanced features including product discharge pumps, multiple in-series staged still unit skid mounted systems and computer/PLC control. As clients’ product production requirements increase, Advanced Synthesis can assist with technology consistent throughout the product line, allowing straightforward process equipment scale up. Equipment for processing 24/7 at more than 200 kg/hr is offered, well more than sufficient for any cannabinoid application.

The Wipe Film Evaporator Unit takes advantage of the fact that each chemical substance has a characteristic vapor pressure. It is this relative difference in vapor pressures which dictates how easily a complex compound can be separated into its constituent components. Since the molecules of all matter are in constant motion in varying degrees, depending upon the chemical composition of that matter and the temperature and pressure applied to it, molecules near the surface have a tendency to escape into the surrounding atmosphere. As temperature increases and pressure decreases, this escaping tendency usually increases and the substance is said to vaporize. The force generated by these escaping molecules is referred to as the vapor pressure of that material at a particular temperature and pressure. It is the relative difference in vapor pressure of substances, which dictates how easily a complex compound can be separated into its constituent compounds.